Search found 99 matches

by ChuckG
Mon 1 Apr 2013 2:39
Forum: Published Studies
Topic: Bb Osp in wild white-tailed deer (NY, Penns.)
Replies: 8
Views: 2268

Re: Bb Osp in wild white-tailed deer (NY, Penns.)

What is OspF, and is it immunogenic in humans?  I need to look into it further, but here's a start: NCBI B31 OspF protein BBR42 Barbour's human/mouse IgG study. Third from bottom, ErpY. BBR42 is mildly immunogenic for late; 14 of 39 positive or 36%. Not for early: 1 of 44 or 2%. For comparison OspC...
by ChuckG
Sun 13 Jan 2013 0:16
Forum: Published Studies
Topic: BBA57 is a Major Trigger of Murine Lyme Arthritis
Replies: 2
Views: 690

Re: BBA57 is a Major Trigger of Murine Lyme Arthritis

BBA57 is mildly immunogenic IgG http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2493225/table/t1/ Infect Immun. 2008 August; 76(8): 3374–3389. Published online 2008 May 12. doi:  10.1128/IAI.00048-08 PMCID: PMC2493225 A Genome-Wide Proteome Array Reveals a Limited Set of Immunogens in Natural Infections...
by ChuckG
Wed 28 Nov 2012 23:52
Forum: Off-Topic Café
Topic: stop and smile
Replies: 2
Views: 1039

Re: stop and smile

This is NOT science! Post it elsewhere.
by ChuckG
Tue 6 Nov 2012 3:08
Forum: Medical Topics
Topic: Borrelia Biofilm Updates: Plos One InVitro ; Boston InVIVo
Replies: 9
Views: 3726

Re: Borrelia Biofilm Updates: Plos One InVitro ; Boston InV

Interesting read. Complete paper. Focus Floating Microscopy “Gold Standard” for Cutaneous Borreliosis? Klaus Eisendle , MD, PhD, Tanja Grabner, MD, and Bernhard Zelger, MD, MSc Abstract Borrelia burgdorferi is difficult to detect in routine biopsy material from patients with skin lesions of borreli...
by ChuckG
Sat 27 Oct 2012 1:05
Forum: Published Studies
Topic: Bb BBK32-dependent vascular adhesion in vivo
Replies: 5
Views: 1575

Re: Bb BBK32-dependent vascular adhesion in vivo

Steere identified BBK32 as p35. Barbour et al 2008 found BBK32 to be strongly immunogenic (IgG) in both early and late lyme. Calculated molecular mass is 40.8 kDa so it is in the shadow of FlaB and BmpA,B,&D.
by ChuckG
Sun 21 Oct 2012 4:35
Forum: Published Studies
Topic: DIVERGENT VIEWS IN THE MOUSE -Bockenstadt versus Barthold
Replies: 14
Views: 2707

Re: DIVERGENT VIEWS IN THE MOUSE -Bockenstadt versus Barthol

Realized a quickie PubMed search might be interesting. Search term: bacterial antigen debris Results: 1 to 20 of 129 [snip] 5. Diverse bacteria promote macrophage foam cell formation via Toll-like receptor-dependent lipid body biosynthesis. Nicolaou G, Goodall AH, Erridge C. J Atheroscler Thromb. 20...
by ChuckG
Thu 18 Oct 2012 1:10
Forum: Off-Topic Café
Topic: New Evidence
Replies: 43
Views: 18153

Re: New Evidence

Off-Topic Café Here you can socialize and have fun with other board members, and talk about all sorts of topics that are not related to Lyme disease. New Evidence by Cobwebby » Sat 8 Sep 2012 19:42 1 2 3 Generally don't visit Off-Topic. I clicked on page 3. There were lawyer jokes. They amused me. ...