Volume 16, Number 3–March 2010
Potential for Tick-borne Bartonelloses
Emmanouil Angelakis, Sarah A. Billeter, Edward B. Breitschwerdt, Bruno B. Chomel, and Didier Raoult
Author affiliations: Université de la Méditerranée, Marseille, France (E. Angelakis, D. Raoult); North Carolina State University College of Veterinary Medicine, Raleigh, North Carolina, USA (S.A. Billeter, E.B. Breitschwerdt); and University of California School of Veterinary Medicine, Davis, California, USA (B.B. Chomel)
As worldwide vectors of human infectious diseases, ticks are considered to be second only to mosquitoes. Each tick species has preferred environmental conditions and biotopes that determine its geographic distribution, the pathogens it vectors, and the areas that pose risk for tick-borne diseases. Researchers have identified an increasing number of bacterial pathogens that are transmitted by ticks, including Anaplasma, Borrelia, Ehrlichia, and Rickettsia spp. Recent reports involving humans and canines suggest that ticks should be considered as potential vectors of Bartonella spp. To strengthen this suggestion, numerous molecular surveys to detect Bartonella DNA in ticks have been conducted. However, there is little evidence that Bartonella spp. can replicate within ticks and no definitive evidence of transmission by a tick to a vertebrate host.
Full article: http://www.cdc.gov/eid/content/16/3/385.htm...
We present an overview of the various Bartonella spp. that have been detected in ticks and discuss human cases of Bartonella infection that are suggestive of tick transmission. Because of the rapidly expanding number of reservoir host–adapted Bartonella spp. that have been discovered in recent years, efforts to clarify modes of transmission are relevant to public health in terms of interrupting the transmission process. As evolving evidence supports the ability of this genus to induce chronic intravascular infections in humans, improved understanding of vector competence could facilitate efforts to block pathogen transmission, which would help improve human health (9).